Endocrine Abstracts

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is showing a rapid and continuous evolution in terms of new waves, the spread of variants and the evidence of reinfections. The growing heterogeneity of clinical presentation requires the identification of underlying pathogenic mechanisms to allow a better risk stratification. Previous studies analysed the role of sex hormones in disease severity demonstrating in male patients the association of...

Background: Patients affected by gastroenteropancreatic-neuroendocrine tumors (GEP-NETs) present an increased risk of bone fragility due to several factors, such as bone metastases, vitamin D deficiency, hormonal secretion, medical and surgical treatments. Although patients with well-differentiated GEP-NETs generally present a long life-expectancy, occurrence of fragility fractures could significantly impair quality of life.Objectives: The study aims to ...

Introduction: Cyclic Cushing’s syndrome (cCS) is a rare condition characterized by periods of excessive cortisol secretion (peaks), alternating with phases of eucortisolism (through). In most cases, cCS is caused by an ACTH-secreting pituitary tumor, while only few cases of cyclic ectopic ACTH secretion (cEAS) have been described.Case presentation: In February 2023, a 58-year-old woman was referred to our Endocrine Unit due to a 10-year history of r...